A link between serum creatinine and muscle in the body, basically not affected by the diet, high catabolism of extrarenal factors, some people will appear blood creatinine and urine creatinine of both at the time of examination, but many people do not know not whether there are differences in serum creatinine and urinary creatinine, following our expert explain the difference between serum creatinine and urinary creatinine.
There may be many patients do not know what is the difference between them two, let us first look at the reasons for high serum creatinine, serum creatinine is due to various causes of infestation in the kidney received after the first appearance renal cell altered phenotype, the formation of pathological changes in the kidney to stimulate the transformation of fibroblasts into myofibroblasts, and invasion and stimulate normal renal tissue inherent in the same lesion, thereby forming a point-to-plane kidney, local to the whole, spread the excitation spread, so has entered the period of organic injury, namely renal injury, this time due to kidney damage caused by time. Excretion function decreased, causing toxins such as creatinine accumulation in the body, so serum creatinine and urea nitrogen increased, urinary creatinine decreased, simple filter decreased speed, etc.
In general, when the glomerular filtration rate dropped to more than 50% of normal serum creatinine, friends were aware of serum creatinine, whereas serum creatinine was significantly higher than that of normal renal function. Because creatinine clearance is affected by glomerular concentration, creatinine is the most reliable indicator of glomerular function in renal failure.
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