Diabetic nephropathy is one of the most important complications of diabetes. And diabetic patients are more likely to suffer from kidney disease, then what factors induce diabetic nephropathy?
Genetic factors: According to relevant studies have shown that in some families with diabetes history of diabetes, the incidence of diabetic nephropathy was significantly higher than patients without family history of hypertension. There is also a difference in the incidence of diabetic nephropathy among different races. This shows that the occurrence of diabetic nephropathy and genetic factors.
Renal blood flow abnormalities: high blood sugar, glomerular hyperperfusion, increased pressure in the case of protein filtration increased, can also be deposited in the glomerular basement membrane, promote matrix proliferation, the formation of a vicious cycle, and can cause knot Arthritis and diffuse glomerulosclerosis.
Hypertension: Hypertension and diabetic nephropathy is not directly related to the occurrence, but the original high blood pressure or course of time to micro-proteinuria when the blood pressure can accelerate the progress of diabetic nephropathy and renal function deterioration, increased urinary albumin discharge.
Hyperglycemia: diabetic nephropathy and hyperglycemia are closely related to poor blood glucose control can accelerate the development of diabetic nephropathy, good blood glucose control can significantly delay its development.
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