How to diagnose early diabetic nephropathy?

At present domestic and foreign widely used radioimmunoassay detection of urinary albumin excretion, is conducive to the discovery of early diabetic nephropathy. It is generally believed that urinary albumin excretion in the continuous urine test for 6 months is 0 ~ 200μg / min (30 ~ 300mg / 24 hours), and other causes of urinary albumin excretion may be ruled out, such as urinary tract infection , Heart failure, exercise, essential hypertension, ketoacidosis, etc., that is diagnosed as early diabetic nephropathy.

Such patients without clinical proteinuria (due to conventional methods can not check the urine protein content) and other clinical manifestations, only showed increased renal volume, accompanied by increased glomerular filtration rate. In recent years, the use of insulin pump to control blood glucose for a long period of time to normal levels, can reduce urinary albumin excretion, renal volume and glomerular filtration rate returned to normal.

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